Conundrums in corneal dystrophies

Conundrums in corneal dystrophies

According to Dr. William Trattler, although corneal dystrophies are rare, they can be successfully managed.

 Dr. Trattler is a refractive, corneal and cataract eye surgeon at the Center For Excellence In Eye Care in Miami, Florida, USA.

Granular corneal dystrophy occurs when deposits slowly form in the middle layer of the cornea of both eyes with age.

 It’s an inherited genetic disease and can cause significant blurring of vision, as well as recurrent corneal erosions and discomfort.

“One of the first challenges is diagnosing granular corneal dystrophy,” explained Dr. Trattler.

 “But now there is a simple test called AvaGen (Avellino, California, USA)

 that can determine the exact diagnosis of anterior corneal dystrophies associated with the TGFBI gene ลาวสามัคคี วีไอพี

and the 70 TGFBI variants.” For such a rare condition, the test is easy, indeed.

 It’s performed by swabbing the inside of the cheek, and results are usually provided within a week.

 Today, there are varying treatment options.

“In the past, corneal transplants were performed, but the challenge is that granular corneal dystrophy can recur in the graft,” said Dr. Trattler.

“Thankfully, there are new procedures that can be performed that can help improve vision and avoid a corneal transplant.”

 One effective treatment is phototherapeutic keratectomy (PTK), which involves smoothing the corneal surface with laser.

Dr. Trattler emphasized that in PTK, the goal is not to laser deeply into the cornea and remove all opacities — rather, the goal is to smooth the cornea.

“At the conclusion of the PTK procedure, it is expected that opacities will be visible in the anterior portion of the cornea.

However, the new smooth surface will result in significant improvement in vision,” he shared.

A once in a lifetime adverse event “There are some cases that are never taught in textbooks — instead,

they require use of every skill and principle of management that you learn while training,” said

Dr. Sahil Thakur, a clinical research fellow for the Ocular Epidemiology Research Group at Singapore Eye Research Institute (SERI) in Singapore.

For more information:  ลาวสามัคคี วีไอพี


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